There is no significant association between history of intravitreal injections (IVI) and posterior capsular rupture (PCR) during cataract surgery, according to a recent study published in the Canadian Journal of Ophthalmology.1
Researchers from the department of ophthalmology, Medical University of Graz, Austria, reviewed 15 years of cataract patient medical records, including a total of 54,046 cataract surgeries in 35,698 patients in their analysis. In addition to IVI, other risk factors investigated included the patients’ age, combined surgery, pseudoexfoliation, surgeon's experience, and the type of cataract surgery performed. After adjusting for confounding risk factors, no statistically significant effect was seen (OR 1.04, 95% CI 0.89-1.21, P= 0.664).
“Our study provides further evidence regarding risk factors for PCR during cataract surgery and possible interdependencies between these risk factors,” the researchers concluded. “Increasing evidence about these risk factors may help in identification of high-risk eyes and in accurate planning of these surgeries to provide the best possible outcome. Further research regarding the influence of confounding factors upon previous IVI as a risk factor for PCR during cataract surgery is needed.”
References
1. Falb T, Singer C, Holter M, et al. Evaluation of intravitreal injections as a risk factor for capsular rupture during cataract surgery. Can J Ophthalmol. Published online June 2, 2024. doi:10.1016/j.jcjo.2024.05.012
